Surveys have Benjamin Netanyahu's Likud Beiteinu list winning 32 to 37 of parliament's 120 seats, making it the best positioned to form Israel's next government.
Former journalist has led her party toward a focus on social and economic issues, leaving its anti-war past behind at a time of strong nationalist sentiment.
President Barack Obama heads into his second term weighed down by an unproductive relationship with the leader of Israel, the bedrock U.S. ally in the Middle East.