The stinging remarks by U.S. National Security Adviser John Bolton follow a fierce war of words between the leaders of the two states at the U.N. General Assembly on Monday.

The Russian defense ministry criticized Israel’s “deliberate provocation” after one of its military planes, with 15 people onboard, was accidentally shot down by allied Syrian forces in Latakia province on Monday.

Iran’s Foreign Minister Javad Zarif hit back at the U.S. on Tuesday over its move to reimpose economic sanctions on the Islamic state, adding that the “world is sick and tired of America’s unilateralism.”

Iran’s President Hassan Rouhani, under pressure over the country’s economic tailspin, denounced the “psychological warfare” by America after a new round of U.S. sanctions against Tehran kicked in on Tuesday.

A coalition of Saudi-led forces launched a fierce offensive on Yemen’s rebel-held port of Hudaydah on Wednesday, in a move that could worsen the humanitarian crisis in the region’s poorest country.

U.N. human rights chief Zeid Raad Al Hussein decried Israel’s use of “wholly disproportionate” force that left some 60 Palestinians dead during border protests along the Gaza frontier earlier this week.

Palestinians are set to hold funerals of 58 protesters killed by Israeli forces on Monday after thousands of infuriated demonstrators had rallied at 13 locations along the Gaza’s eastern border.

U.S. officials and President Donald Trump’s daughter Ivanka are in Israel to attend the inauguration of the U.S. embassy in Jerusalem, as Israeli forces gear up to tackle violent protesters rallying along the Gaza Strip frontier.

French Foreign Minister Jean-Yves Le Drian decried the “extraterritoriality” of Washington’s decision to reintroduce sanctions on companies trading with Iran, calling the move "unacceptable."

Israel passed a controversial law that defines the country as an exclusively Jewish state, a move critics fear would tear apart its democratic framework by reinforcing biases against its 1.8m Palestinian citizens.